The Case for Treating Cholesterol Before Plaque Appears | Dr Thomas Dayspring and Dr Dan Soffer
Most people are told their cholesterol is normal and take that as an all clear. Dr Thomas Dayspring and Dr Daniel Soffer would like a word. Both are Masters of the National Lipid Association, both have spent their careers inside the science of lipids and atherosclerosis, and both joined me to talk about the part […]
Bone Health, Falls, Medications & Healthy Longevity | Dr Deborah Kado
At a dinner party, everyone wants to talk about longevity. Almost no one wants to talk about gerontology. My guest today, Dr Deborah Kado, has spent more than three decades in the field that longevity science quietly rebranded, and she brings a perspective the supplement stacks and biological age tests tend to miss. Deborah is […]
Type 2 Diabetes Remission in the GLP-1 Era | Prof Roy Taylor
Three years after our first conversation, Professor Roy Taylor returns with the strongest evidence yet that type 2 diabetes is a reversible condition. The five-year results of his DiRECT trial are in, the NHS has built a national remission programme on his work, and the picture is now remarkably clear: lose enough weight to get […]
Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess
What if you could lower your blood glucose more than medication can, without losing a single kilogram? In this episode, I sit down with Dr Nicola Guess, a registered dietitian and Senior Research Fellow at the University of Oxford, whose research is challenging some of the most entrenched ideas in type 2 diabetes care. The […]
The Fertility Test Most Men Are Never Offered | Dr Michael Eisenberg and Dr Natalie Crawford
In this episode I’m joined by two clinicians who sit on either side of the same problem: Dr Michael Eisenberg, a urologist, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, and Dr Natalie Crawford, a reproductive endocrinologist and co-founder of Fora Fertility in Austin, Texas. Natalie came on the […]
Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson
Dr Terry Simpson is back, and this time we cover a lot of ground. He is a surgeon with a background in molecular biology, critical care, and nutrition who has become one of the clearest voices online for separating good science from confident nonsense. In this conversation we move from the new generation of cholesterol-lowering […]
The Science of Metabolic Flexibility, Zone 2, and Reversing Diabetes | A Masterclass
Metabolic flexibility is one of those ideas that sits quietly underneath almost everything we talk about when it comes to health, yet very few of us have ever had it explained clearly. In this masterclass I have brought together some of the sharpest minds in metabolism, exercise physiology, and diabetes research to unpack what metabolic […]
New Science of Weight Loss | A Masterclass
GLP-1 medications are changing the conversation around obesity, but are they really a magic bullet? In this masterclass, I bring together insights from leading experts to unpack how these medications work, who they’re for, and why long-term success still depends on nutrition, exercise, and addressing the food environment. Drawing on conversations with Dr Terry Simpson, […]
Fertility, Sperm Health, and Nutrition Before and During Pregnancy | Dr Federica Amati
In this episode I’m joined again by Dr Federica Amati, Head Nutritionist at ZOE and one of the clearest voices I know on how food shapes our health across a lifetime. This time we focus on fertility, preconception health, and nutrition through pregnancy, the opening chapters of what researchers call the first 1,000 days, the window […]
Can You Reverse Heart Disease? What My Plaque Scans Showed | Dr Campbell Rogers
In this episode I sit down with Dr Campbell Rogers, an interventional cardiologist who trained at Harvard, ran the cardiac catheterisation lab at Brigham and Women’s Hospital, and now serves as Chief Medical Officer at Heartflow. The reason I wanted to speak with him is personal. In late 2024 I had a CT coronary angiogram […]
